~Karbadust Reg. No. L0493 G0196 N-AR0148 Act No. 36 of 1947 W130190 Insecticide dusting powder for home garden and animal use. A residual contact and stomach poison for the control of pests as listed. Features: Can be used on Dogs & Cats to control Ticks and Fleas Sizes: 200 g | 500 g How does it work? Carbaryl acts on the nervous system of the parasites as inhibitor of acetylcholinesterase (also known as AchE), an enzyme that hydrolyzes acetylcholine (Ach). Ach is a molecule involved in the transmission of nervous signals from nerves to muscles (so-called neuromuscular junctions) and between neurons in the brain (so-called cholinergic brain synapses). AchE’s role is to terminate the transmission of nervous signals where Ach is the neurotransmitter (there are several other neurotransmitters). By inhibiting the activity of AchE, carbaryl prevent the termination of those nervous signals, i.e. the neurons remain in constant activity and excitation, massively disturbing the normal movements of the parasites. The bottom line for the parasites is that they are paralyzed and die more or less quickly. Where can it be used? Dogs, cats, poultry, birds, lawns and ornamentals.