~Monthly application of Advocate helps protect your dog against a broad spectrum of parasites. An easy-to-use spot-on, Advocate is applied monthly to both help rid your dog of existing parasites and provide ongoing protection. The powerful ingredients in Advocate provide fast relief from fleas, prevent deadly heartworm and help protect your dog and your family from most intestinal worms including roundworms, hookworms and whipworm. Stop fleas in their tracks The active ingredient effective against fleas, imidacloprid, spreads across your dog’s skin and coat within 12 hours. After this time, re-infesting fleas are affected within 3-5 minutes of contact with your dog, and killed within 1 hour. Unlike chewable tablets, the active ingredient is not absorbed into your dog’s bloodstream, so fleas are killed on contact without the need for a blood meal. As your dog naturally sheds their skin and fur, tiny imidacloprid crystals are also shed into the environment, killing flea larvae, and breaking the flea lifecycle.